{"id":4624,"date":"2021-03-13T07:32:59","date_gmt":"2021-03-13T07:32:59","guid":{"rendered":"https:\/\/tmckolkata.com\/in\/?page_id=4624"},"modified":"2025-01-04T07:12:14","modified_gmt":"2025-01-04T07:12:14","slug":"department-of-cytogenetics","status":"publish","type":"page","link":"https:\/\/tmckolkata.com\/in\/department-of-cytogenetics\/","title":{"rendered":"Department of Cytogenetics"},"content":{"rendered":"<div id='av-layout-grid-1'  class='av-layout-grid-container av-koaw87th-2577361a65c281b5c32f69ecafc94e4e entry-content-wrapper main_color av-flex-cells  avia-builder-el-0  el_before_av_layout_row  avia-builder-el-first   container_wrap sidebar_right'  >\n\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-koaw8itx-1e5b275a207906bed08d93739ad1b66a\">\n.flex_cell.av-koaw8itx-1e5b275a207906bed08d93739ad1b66a{\nvertical-align:middle;\nheight:400px;\nmin-height:400px;\nbackground:url(https:\/\/tmckolkata.com\/in\/wp-content\/uploads\/2021\/05\/Cyto1.jpg) 0% 0% no-repeat scroll ;\n}\n.responsive #top #wrap_all .flex_cell.av-koaw8itx-1e5b275a207906bed08d93739ad1b66a{\npadding:80px 80px 80px 80px !important;\n}\n<\/style>\n<div class='flex_cell av-koaw8itx-1e5b275a207906bed08d93739ad1b66a av-gridrow-cell av_one_half no_margin  avia-builder-el-1  el_before_av_cell_one_half  avia-builder-el-first  content-align-middle avia-full-stretch'  ><div class='flex_cell_inner'>\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-koawpo2n-813de8e503f1f819722f3dfab67d5e4d\">\n#top .av-special-heading.av-koawpo2n-813de8e503f1f819722f3dfab67d5e4d{\npadding-bottom:10px;\nfont-size:40px;\n}\nbody .av-special-heading.av-koawpo2n-813de8e503f1f819722f3dfab67d5e4d .av-special-heading-tag .heading-char{\nfont-size:25px;\n}\n#top #wrap_all .av-special-heading.av-koawpo2n-813de8e503f1f819722f3dfab67d5e4d .av-special-heading-tag{\nfont-size:40px;\n}\n.av-special-heading.av-koawpo2n-813de8e503f1f819722f3dfab67d5e4d .av-subheading{\nfont-size:15px;\n}\n\n@media only screen and (min-width: 480px) and (max-width: 767px){ \n#top #wrap_all .av-special-heading.av-koawpo2n-813de8e503f1f819722f3dfab67d5e4d .av-special-heading-tag{\nfont-size:0.8em;\n}\n}\n\n@media only screen and (max-width: 479px){ \n#top #wrap_all .av-special-heading.av-koawpo2n-813de8e503f1f819722f3dfab67d5e4d .av-special-heading-tag{\nfont-size:0.8em;\n}\n}\n<\/style>\n<div  class='av-special-heading av-koawpo2n-813de8e503f1f819722f3dfab67d5e4d av-special-heading-h3 blockquote modern-quote  avia-builder-el-2  avia-builder-el-no-sibling  av-inherit-size'><h3 class='av-special-heading-tag '  itemprop=\"headline\"  >Department of Cytogenetics<\/h3><div class='av-subheading av-subheading_below'><p>Department of Laboratory Sciences<\/p>\n<\/div><div class=\"special-heading-border\"><div class=\"special-heading-inner-border\"><\/div><\/div><\/div>\n<\/div><\/div>\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-koawaecc-741ede44ac30c9c641aaefe8984aeb84\">\n.flex_cell.av-koawaecc-741ede44ac30c9c641aaefe8984aeb84{\nvertical-align:middle;\nheight:400px;\nmin-height:400px;\nbackground:url(https:\/\/tmckolkata.com\/in\/wp-content\/uploads\/2021\/05\/Cyto.jpg) 0% 0% no-repeat scroll ;\n}\n.responsive #top #wrap_all .flex_cell.av-koawaecc-741ede44ac30c9c641aaefe8984aeb84{\npadding:80px 80px 80px 80px !important;\n}\n<\/style>\n<div class='flex_cell av-koawaecc-741ede44ac30c9c641aaefe8984aeb84 av-gridrow-cell av_one_half no_margin  avia-builder-el-3  el_after_av_cell_one_half  avia-builder-el-last  content-align-middle avia-full-stretch'  ><div class='flex_cell_inner'><\/div><\/div>\n<\/div>\n<div id='av-layout-grid-2'  class='av-layout-grid-container av-9643n4-27a3307b2d88fbb2b7d5261f1e738237 entry-content-wrapper main_color av-flex-cells  avia-builder-el-4  el_after_av_layout_row  el_before_av_section  grid-row-not-first  container_wrap sidebar_right'  >\n\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-koawrg2o-1ec0a7d42d405cacb6ca2b891afeeca5\">\n.flex_cell.av-koawrg2o-1ec0a7d42d405cacb6ca2b891afeeca5{\nvertical-align:middle;\nbackground-color:#2388c2;\n}\n.responsive #top #wrap_all .flex_cell.av-koawrg2o-1ec0a7d42d405cacb6ca2b891afeeca5{\npadding:15px 15px 15px 15px !important;\n}\n<\/style>\n<div class='flex_cell av-koawrg2o-1ec0a7d42d405cacb6ca2b891afeeca5 av-gridrow-cell av_one_fourth no_margin  avia-builder-el-5  el_before_av_cell_one_fourth  avia-builder-el-first  content-align-middle'  ><div class='flex_cell_inner'><\/div><\/div>\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-koawrvy5-98007e265845a3f36f513bdcb48f31af\">\n.flex_cell.av-koawrvy5-98007e265845a3f36f513bdcb48f31af{\nvertical-align:middle;\nbackground-color:#379cd6;\n}\n.responsive #top #wrap_all .flex_cell.av-koawrvy5-98007e265845a3f36f513bdcb48f31af{\npadding:15px 15px 15px 15px !important;\n}\n<\/style>\n<div class='flex_cell av-koawrvy5-98007e265845a3f36f513bdcb48f31af av-gridrow-cell av_one_fourth no_margin  avia-builder-el-6  el_after_av_cell_one_fourth  el_before_av_cell_one_fourth  content-align-middle'  ><div class='flex_cell_inner'><\/div><\/div>\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-koawsav1-49fcf4e1b28035a3ffcca9dd1c8417a3\">\n.flex_cell.av-koawsav1-49fcf4e1b28035a3ffcca9dd1c8417a3{\nvertical-align:middle;\nbackground-color:#5fb4e4;\n}\n.responsive #top #wrap_all .flex_cell.av-koawsav1-49fcf4e1b28035a3ffcca9dd1c8417a3{\npadding:15px 15px 15px 15px !important;\n}\n<\/style>\n<div class='flex_cell 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avia-builder-el-10  el_before_av_three_fifth  avia-builder-el-first '><h4 class='av-special-heading-tag '  itemprop=\"headline\"  >Department of Cytogenetics<\/h4><div class=\"special-heading-border\"><div class=\"special-heading-inner-border\"><\/div><\/div><\/div>\n\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-1v07zk-cc490ebecc9981670793a668a1f311b6\">\n.flex_column.av-1v07zk-cc490ebecc9981670793a668a1f311b6{\nborder-radius:0px 0px 0px 0px;\npadding:0px 0px 0px 0px;\n}\n<\/style>\n<div  class='flex_column av-1v07zk-cc490ebecc9981670793a668a1f311b6 av_three_fifth  avia-builder-el-11  el_after_av_heading  el_before_av_two_fifth  first flex_column_div av-zero-column-padding  '     ><section  class='av_textblock_section av-km4u32bo-68e10f0c00c66c521158ce898d58aadd '   itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/CreativeWork\" ><div class='avia_textblock'  itemprop=\"text\" ><p><strong>About the Department<\/strong><\/p>\n<p style=\"text-align: justify;\">The Cytogenetics laboratory at TMC is a the only NABL accredited state-of-the-art laboratory in Eastern India which provides comprehensive cytogenetic services in both haematological malignancies and solid tumors.<\/p>\n<p style=\"text-align: justify;\">Cytogenetic characterization of tumors plays a pivotal role in the diagnosis, risk stratification, prognosis, therapeutic selection and monitoring of treatment in various hematological and solid malignancies. The laboratory handles more than 3000 samples annually that include peripheral blood, bone marrow and solid tumor tissue samples. The department organizes numerous CMEs and workshops and has trained people in India and abroad helping them set up cytogenetic laboratories. The team has formulated efficient cost effective strategies and algorithms to genomically characterize tumor cells that can be applied in low resource settings.\u00a0 Their work has resulted in numerous publications in national and international peer reviewed journals.<\/p>\n<\/div><\/section><\/div>\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-5bjglc-c1a1f86cf55f6a902a0ffc5af6dae22d\">\n.flex_column.av-5bjglc-c1a1f86cf55f6a902a0ffc5af6dae22d{\nborder-radius:0px 0px 0px 0px;\npadding:0px 0px 0px 0px;\n}\n<\/style>\n<div  class='flex_column av-5bjglc-c1a1f86cf55f6a902a0ffc5af6dae22d av_two_fifth  avia-builder-el-13  el_after_av_three_fifth  el_before_av_heading  flex_column_div av-zero-column-padding  '     ><p>\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-koawzo5q-958c5b9467e6c282f57b222c9f2ae286\">\n#top .hr.hr-invisible.av-koawzo5q-958c5b9467e6c282f57b222c9f2ae286{\nheight:60px;\n}\n<\/style>\n<div  class='hr av-koawzo5q-958c5b9467e6c282f57b222c9f2ae286 hr-invisible  avia-builder-el-14  el_before_av_image  avia-builder-el-first '><span class='hr-inner '><span class=\"hr-inner-style\"><\/span><\/span><\/div><br \/>\n\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-koawxarh-b2c3f9e08e0b800ca455925178571543\">\n.avia-image-container.av-koawxarh-b2c3f9e08e0b800ca455925178571543 img.avia_image{\nbox-shadow:none;\n}\n.avia-image-container.av-koawxarh-b2c3f9e08e0b800ca455925178571543 .av-image-caption-overlay-center{\ncolor:#ffffff;\n}\n<\/style>\n<div  class='avia-image-container av-koawxarh-b2c3f9e08e0b800ca455925178571543 av-styling- av-hover-grow avia-align-center  avia-builder-el-15  el_after_av_hr  avia-builder-el-last '   itemprop=\"image\" itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/ImageObject\" ><div class=\"avia-image-container-inner\"><div class=\"avia-image-overlay-wrap\"><img decoding=\"async\" fetchpriority=\"high\" class='wp-image-4696 avia-img-lazy-loading-not-4696 avia_image ' src=\"https:\/\/tmckolkata.com\/in\/wp-content\/uploads\/2021\/03\/Group-PHoto-department1.jpg\" alt='' title='Group PHoto department1'  height=\"450\" width=\"800\"  itemprop=\"thumbnailUrl\" srcset=\"https:\/\/tmckolkata.com\/in\/wp-content\/uploads\/2021\/03\/Group-PHoto-department1.jpg 800w, https:\/\/tmckolkata.com\/in\/wp-content\/uploads\/2021\/03\/Group-PHoto-department1-300x169.jpg 300w, https:\/\/tmckolkata.com\/in\/wp-content\/uploads\/2021\/03\/Group-PHoto-department1-768x432.jpg 768w, https:\/\/tmckolkata.com\/in\/wp-content\/uploads\/2021\/03\/Group-PHoto-department1-705x397.jpg 705w\" sizes=\"(max-width: 800px) 100vw, 800px\" \/><\/div><\/div><\/div><\/p><\/div>\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-2yujsg-f633aaa90ce6e0b5c85ae92e0ba7385d\">\n#top .av-special-heading.av-2yujsg-f633aaa90ce6e0b5c85ae92e0ba7385d{\nmargin:10px 10px 10px 10px;\npadding-bottom:1px;\n}\nbody .av-special-heading.av-2yujsg-f633aaa90ce6e0b5c85ae92e0ba7385d .av-special-heading-tag .heading-char{\nfont-size:25px;\ncolor:#21759b;\npadding-bottom:1px;\n}\nbody .av-special-heading.av-2yujsg-f633aaa90ce6e0b5c85ae92e0ba7385d .av-special-heading-tag .heading-char.avia-svg-icon svg:first-child{\nfill:#21759b;\nstroke:#21759b;\n}\n.av-special-heading.av-2yujsg-f633aaa90ce6e0b5c85ae92e0ba7385d .av-subheading{\nfont-size:15px;\n}\n<\/style>\n<div  class='av-special-heading av-2yujsg-f633aaa90ce6e0b5c85ae92e0ba7385d av-special-heading-h3 custom-color-heading blockquote elegant-quote elegant-centered  avia-builder-el-16  el_after_av_two_fifth  el_before_av_textblock  av-thin-font av-icon'><h3 class='av-special-heading-tag '  itemprop=\"headline\"  ><span class='heading-char avia-iconfont avia-font-entypo-fontello' data-av_icon='\ue817' data-av_iconfont='entypo-fontello' ><\/span><span class=\"heading-wrap\"><strong>Facilities<\/strong><\/span><\/h3><div class=\"special-heading-border\"><div class=\"special-heading-inner-border\"><\/div><\/div><\/div>\n<section  class='av_textblock_section av-km68auin-d9f6e9c7aa921fd67fbcbd64d346bd97 '   itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/CreativeWork\" ><div class='avia_textblock'  itemprop=\"text\" ><p style=\"text-align: justify;\">The department has three automated karyotyping and FISH workstations with automated scanning and Imaging Platform for automatic capture of metaphases as well as aautomated fluorescence in-situ hybridization analysis (FISH signal counting).<\/p>\n<p style=\"text-align: justify;\">The laboratory performs karyotyping on hematological malignancies along with Fluorescent in situ hybridisaiton (FISH). Solid tumors are studied by performing FISH analysis on formalin fixed paraffin embedded tissue sections as well as cell blocks and cytology smears.\u00a0 Along with stress cytogenetics the department has also used high density arrays to characterize copy number variations in acute leukaemias.<\/p>\n<p><br class=\"avia-permanent-lb\" \/><strong>List of FISH Probes available<\/strong><\/p>\n<\/div><\/section>\n<div  class='togglecontainer av-km775mo2-a5be1d2fd9fbe64d24d33ddd82663111  avia-builder-el-18  el_after_av_textblock  el_before_av_hr  toggle_close_all' >\n<section class='av_toggle_section av-km7746y5-99b070e92b161d81dcff148a3ef790ba'  itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/CreativeWork\" ><div role=\"tablist\" class=\"single_toggle\" data-tags=\"{All} \"  ><p id='toggle-toggle-id-1' data-fake-id='#toggle-id-1' class='toggler  av-title-above '  itemprop=\"headline\"  role='tab' tabindex='0' aria-controls='toggle-id-1' data-slide-speed=\"200\" data-title=\"FISH (Fluorescence in situ hybridization) - Hematological Malignancies:\" data-title-open=\"\" data-aria_collapsed=\"Click to expand: FISH (Fluorescence in situ hybridization) - Hematological Malignancies:\" data-aria_expanded=\"Click to collapse: FISH (Fluorescence in situ hybridization) - Hematological Malignancies:\">FISH (Fluorescence in situ hybridization) - Hematological Malignancies:<span class=\"toggle_icon\"><span class=\"vert_icon\"><\/span><span class=\"hor_icon\"><\/span><\/span><\/p><div id='toggle-id-1' aria-labelledby='toggle-toggle-id-1' role='region' class='toggle_wrap  av-title-above'  ><div class='toggle_content invers-color '  itemprop=\"text\" ><table width=\"0\">\n<tbody>\n<tr>\n<td colspan=\"4\" width=\"688\"><strong>B-CELL ACUTE LYMPHOBLASTIC LEUKEMIA<\/strong><\/td>\n<\/tr>\n<tr>\n<td width=\"196\"><\/td>\n<td width=\"161\"><strong>Hyper\/Hypodiploidy <\/strong><\/td>\n<td width=\"123\"><strong><em>Ph Like ALL<\/em><\/strong><\/td>\n<td width=\"208\"><strong><em>B &#8211; Others<\/em><\/strong><\/td>\n<\/tr>\n<tr>\n<td width=\"196\">\u2022\u00a0\u00a0 <em>ETV6\/RUNX1 &#8211; t(12;21)<\/em><\/p>\n<p>\u2022\u00a0\u00a0 <em>BCR\/ABL1- t(9;22)<\/em><\/p>\n<p>\u2022\u00a0\u00a0 <em>KMT2A\/MLL-11q23v<\/em><\/p>\n<p>\u2022\u00a0\u00a0 <em>E2A<\/em><\/p>\n<p>\u2022\u00a0\u00a0 <em>E2A\/PBX1\/HLF <\/em><\/td>\n<td width=\"161\">\u2022\u00a0\u00a0 CEP 4<\/p>\n<p>\u2022\u00a0\u00a0 CEP 10<\/p>\n<p>\u2022\u00a0\u00a0 CEN 17<\/p>\n<p>\u2022\u00a0\u00a0 7\/15\/17<\/td>\n<td width=\"123\">\u2022\u00a0\u00a0 <em>ABL1<\/em><\/p>\n<p>\u2022\u00a0\u00a0 <em>ABL2<\/em><\/p>\n<p>\u2022\u00a0\u00a0 <em>CRLF2<\/em><\/p>\n<p>\u2022\u00a0\u00a0 <em>CSF1R<\/em><\/p>\n<p>\u2022\u00a0\u00a0 <em>EPOR1<\/em><\/p>\n<p>\u2022\u00a0\u00a0 <em>JAK2<\/em><\/p>\n<p>\u2022\u00a0\u00a0 <em>NTRK3<\/em><\/p>\n<p>\u2022\u00a0\u00a0 <em>PDGFRB<\/em><\/td>\n<td width=\"208\">\u2022\u00a0\u00a0 <em>ETV6<\/em><\/p>\n<p>\u2022\u00a0\u00a0 <em>IgH<\/em><\/p>\n<p>\u2022\u00a0\u00a0 <em>CDKN2A<\/em><\/p>\n<p>\u2022\u00a0\u00a0 <em>cMYC <\/em><\/p>\n<p>\u2022\u00a0\u00a0 <em>IgH\/cMYC <\/em><\/p>\n<p>\u2022\u00a0\u00a0 <em>ZNF384<\/em><\/p>\n<p>\u2022\u00a0\u00a0 <em>MEF2D\/BCL9<\/em><\/p>\n<p>\u2022\u00a0\u00a0 <em>Sub telomeric 21 \u2013 iAMP21<\/em><\/td>\n<\/tr>\n<tr>\n<td colspan=\"4\" width=\"688\"><strong>T-CELL ACUTE LYMPHOBLASTIC LEUKEMIA<\/strong><\/td>\n<\/tr>\n<tr>\n<td colspan=\"4\" width=\"688\">\u2022\u00a0\u00a0 <em>BCR\/ABL1- t(9;22)<\/em><\/p>\n<p>\u2022\u00a0\u00a0 <em>ABL1<\/em><\/p>\n<p>\u2022\u00a0\u00a0 <em>KMT2A\/MLL-11q23v<\/em><\/p>\n<p>\u2022\u00a0\u00a0 <em>NUP98<\/em><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<table width=\"0\">\n<tbody>\n<tr>\n<td colspan=\"3\" width=\"404\"><strong><em>MULTIPLE MYELOMA*<\/em><\/strong><\/td>\n<td rowspan=\"2\" width=\"19\"><strong><em>\u00a0<\/em><\/strong><\/td>\n<td width=\"265\"><strong><em>CHRONIC LYMPHOCYTIC LEUKEMIA <\/em><\/strong><\/td>\n<td width=\"1\"><\/td>\n<\/tr>\n<tr>\n<td width=\"243\">\u2022\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 <em>TP53\/CEN 17<\/em><\/p>\n<p>\u2022\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 <em>IgH<\/em><\/p>\n<p>\u2022\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 <em>CDKN2C\/CKS1B -1p32\/1q21<\/em><\/p>\n<p>\u2022\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 <em>5p15\/9q22\/15q22<\/em><\/p>\n<p><strong><em>*CD138 Enriched <\/em><\/strong><\/td>\n<td colspan=\"2\" width=\"161\">\u2022\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 <em>IgH\/FGFR3-t(4;14)<\/em><\/p>\n<p>\u2022\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 <em>IgH\/CCND3-t(6;14)<\/em><\/p>\n<p>\u2022\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 <em>IgH\/cMYC \u2013t(8;14)<\/em><\/p>\n<p>\u2022\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 <em>IgH\/CCND1-t(11;14)<\/em><\/p>\n<p>\u2022\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 <em>IgH\/MAF-t(14;16)<\/em><\/p>\n<p>\u2022\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 <em>IgH\/MAFB-t(14;20)<\/em><\/td>\n<td width=\"265\">\u2022\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 <em>TP53<\/em><\/p>\n<p>\u2022\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 <em>ATM <\/em><\/p>\n<p>\u2022\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 <em>CEP12<\/em><\/p>\n<p>\u2022\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 <em>RB1\/13q<\/em><\/td>\n<td width=\"1\"><\/td>\n<\/tr>\n<tr>\n<td colspan=\"6\" width=\"688\"><strong>ACUTE MYELOID LEUKEMIA<\/strong><\/td>\n<\/tr>\n<tr>\n<td colspan=\"2\" width=\"345\">\u2022\u00a0\u00a0 <em>AML1\/ETO t(8;21) <\/em><\/p>\n<p>\u2022\u00a0\u00a0 <em>CBFb \u2013 inv(16) or t(16;16)<\/em><\/p>\n<p>\u2022\u00a0\u00a0 <em>PML\/RAR<\/em><em>\u03b1<\/em><em> t(15;17) <\/em><\/p>\n<p>\u2022\u00a0\u00a0 <em>RAR<\/em><em>\u03b1<\/em><\/p>\n<p>\u2022\u00a0\u00a0 <em>BCR\/ABL1 &#8211; t(9;22)<\/em><\/p>\n<p>\u2022\u00a0\u00a0 <em>KMT2A\/MLL &#8211; 11q23<\/em><\/p>\n<p>\u2022\u00a0\u00a0 <em>KMT2A\/MLLT3 &#8211; t(9;11)<\/em><\/p>\n<p>\u2022\u00a0\u00a0 <em>NUP98<\/em><\/td>\n<td colspan=\"4\" width=\"343\">\u2022\u00a0\u00a0 <em>GATA2-MECOM <\/em>3q<\/p>\n<p>\u2022\u00a0\u00a0 Del 5q<\/p>\n<p>\u2022\u00a0\u00a0 CEP7\/Del 7q<\/p>\n<p>\u2022\u00a0\u00a0 <em>TP53<\/em>\/CEN 17<\/p>\n<p>\u2022\u00a0\u00a0 20q12 \u2013 <em>PTPRT<\/em><\/p>\n<p>\u2022\u00a0\u00a0 CEP 8<\/td>\n<\/tr>\n<tr>\n<td width=\"243\"><\/td>\n<td width=\"101\"><\/td>\n<td width=\"59\"><\/td>\n<td width=\"19\"><\/td>\n<td width=\"265\"><\/td>\n<td width=\"1\"><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<table width=\"0\">\n<tbody>\n<tr>\n<td width=\"334\"><strong><em>MYELODYSPLASTIC SYNDROME<\/em><\/strong><\/td>\n<td width=\"353\"><strong><em>MYELOPROLIFERATIVE NEOPLASM<\/em><\/strong><\/td>\n<\/tr>\n<tr>\n<td width=\"334\">\u2022\u00a0\u00a0 <em>GATA2-MECOM 3q<\/em><\/p>\n<p>\u2022\u00a0\u00a0 <em>Del 5q<\/em><\/p>\n<p>\u2022\u00a0\u00a0 <em>CEP7\/Del 7q<\/em><\/p>\n<p>\u2022\u00a0\u00a0 <em>TP53\/CEN 17<\/em><\/p>\n<p>\u2022\u00a0\u00a0 <em>20q12 \u2013 PTPRT<\/em><\/p>\n<p>\u2022\u00a0\u00a0 <em>KMT2A\/MLL &#8211; 11q23<\/em><\/p>\n<p>\u2022\u00a0\u00a0 CEP 8<\/td>\n<td width=\"353\">\u2022\u00a0\u00a0 <em>BCR\/ABL1 &#8211; t(9;22)<\/em><\/p>\n<p>\u2022\u00a0\u00a0 <em>PDGFRA\/FIP1L1\/CHIC2<\/em><\/p>\n<p>\u2022\u00a0\u00a0 <em>PDGFRb <\/em><\/p>\n<p>\u2022\u00a0\u00a0 <em>FGFR1<\/em><\/p>\n<p>\u2022\u00a0\u00a0 <em>JAK2<\/em><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<table width=\"0\">\n<tbody>\n<tr>\n<td width=\"682\">\u2022\u00a0\u00a0 CEP XX\/XY in Opposite Sex Bone Marrow Transplant <strong>(BMT)<\/strong><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div><\/div><\/div><\/section>\n<section class='av_toggle_section av-km775abx-f05fb653673f42562f79dcffacb72b23'  itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/CreativeWork\" ><div role=\"tablist\" class=\"single_toggle\" data-tags=\"{All} \"  ><p id='toggle-toggle-id-2' data-fake-id='#toggle-id-2' class='toggler  av-title-above '  itemprop=\"headline\"  role='tab' tabindex='0' aria-controls='toggle-id-2' data-slide-speed=\"200\" data-title=\"FISH (Fluorescence in situ hybridization) - Solid Malignancies:\" data-title-open=\"\" data-aria_collapsed=\"Click to expand: FISH (Fluorescence in situ hybridization) - Solid Malignancies:\" data-aria_expanded=\"Click to collapse: FISH (Fluorescence in situ hybridization) - Solid Malignancies:\">FISH (Fluorescence in situ hybridization) - Solid Malignancies:<span class=\"toggle_icon\"><span class=\"vert_icon\"><\/span><span class=\"hor_icon\"><\/span><\/span><\/p><div id='toggle-id-2' aria-labelledby='toggle-toggle-id-2' role='region' class='toggle_wrap  av-title-above'  ><div class='toggle_content invers-color '  itemprop=\"text\" ><table width=\"0\">\n<tbody>\n<tr>\n<td width=\"196\"><strong><em>Ca Breast\/Gastric<\/em><\/strong><\/td>\n<td width=\"142\"><strong><em>Ca Lung<\/em><\/strong><\/td>\n<td width=\"161\"><strong><em>CNS Tumour<\/em><\/strong><\/td>\n<\/tr>\n<tr>\n<td width=\"196\">\u2022\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 <em>CEN 17\/ERBB2 <\/em><\/td>\n<td width=\"142\">\u2022\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 <em>ALK<\/em><\/p>\n<p>\u2022\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 <em>ROS1<\/em><\/p>\n<p>\u2022\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 <em>MET<\/em><\/p>\n<p>\u2022\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 <em>RET<\/em><\/td>\n<td width=\"161\">\u2022\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 <em>1p\/19q<\/em><\/p>\n<p>\u2022\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 <em>MYCN<\/em><\/p>\n<p>\u2022\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 <em>cMYC\/CEN8<\/em><\/p>\n<p>\u2022\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 <em>TP53\/CEN 17<\/em><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<table width=\"0\">\n<tbody>\n<tr>\n<td width=\"196\"><strong><em>Lymphoma<\/em><\/strong><\/td>\n<td width=\"142\"><strong><em>Sarcoma<\/em><\/strong><\/td>\n<td width=\"19\"><strong><em>\u00a0<\/em><\/strong><\/td>\n<td width=\"105\"><strong><em>Renal Cell Ca<\/em><\/strong><\/td>\n<td width=\"178\"><strong><em>Mammary Analogue Ca<\/em><\/strong><\/td>\n<\/tr>\n<tr>\n<td width=\"196\">\u2022\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 <em>cMYC <\/em><\/p>\n<p>\u2022\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 <em>BCL6 <\/em><\/p>\n<p>\u2022\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 <em>BCL2<\/em><\/p>\n<p>\u2022\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 <em>\u00a0IgH<\/em><\/p>\n<p>\u2022\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 <em>cMYC-IGH<\/em><\/p>\n<p>\u2022\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 <em>BCL2-IGH<\/em><\/p>\n<p>\u2022\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 <em>CCND1\/IGH <\/em><\/p>\n<p>\u2022\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 <em>IRF4, DUSP22 <\/em><\/td>\n<td width=\"142\">\u2022\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 <em>FOXO1<\/em><\/p>\n<p>\u2022\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 <em>MDM2\/CEN 12<\/em><\/p>\n<p>\u2022\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 <em>RET <\/em><\/p>\n<p>\u2022\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 <em>FUS <\/em><\/p>\n<p>\u2022\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 <em>SS18\/SYT<\/em><\/p>\n<p>\u2022\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 <em>EWSR1 <\/em><\/td>\n<td width=\"19\"><em>\u00a0<\/em><\/td>\n<td width=\"105\">\u2022\u00a0\u00a0 <em>TFE3<\/em><\/p>\n<p>\u2022\u00a0\u00a0 <em>NTRK3<\/em><\/td>\n<td width=\"178\">\u2022\u00a0\u00a0 <em>ETV6<\/em><\/p>\n<p>\u2022\u00a0\u00a0 <em>NTRK3<\/em><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div><\/div><\/div><\/section>\n<\/div>\n\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-koayosa7-c1a6044281e4699cde1ab4397bfc60f3\">\n#top .hr.hr-invisible.av-koayosa7-c1a6044281e4699cde1ab4397bfc60f3{\nheight:10px;\n}\n<\/style>\n<div  class='hr av-koayosa7-c1a6044281e4699cde1ab4397bfc60f3 hr-invisible  avia-builder-el-19  el_after_av_toggle_container  el_before_av_one_third '><span class='hr-inner '><span class=\"hr-inner-style\"><\/span><\/span><\/div>\n\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-58jv4w-f1e17a6ff3d72032fa432bee65a835b2\">\n.flex_column.av-58jv4w-f1e17a6ff3d72032fa432bee65a835b2{\nborder-radius:0px 0px 0px 0px;\npadding:0px 0px 0px 0px;\n}\n<\/style>\n<div  class='flex_column av-58jv4w-f1e17a6ff3d72032fa432bee65a835b2 av_one_third  avia-builder-el-20  el_after_av_hr  el_before_av_one_third  first flex_column_div av-zero-column-padding  '     ><p>\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-km7dq8n6-65a32f4a104562054d89134e2c935873\">\n.avia-image-container.av-km7dq8n6-65a32f4a104562054d89134e2c935873 img.avia_image{\nbox-shadow:none;\n}\n.avia-image-container.av-km7dq8n6-65a32f4a104562054d89134e2c935873 .av-image-caption-overlay-center{\ncolor:#ffffff;\n}\n<\/style>\n<div  class='avia-image-container av-km7dq8n6-65a32f4a104562054d89134e2c935873 av-styling- av-hover-grow avia-align-center  avia-builder-el-21  el_before_av_image  avia-builder-el-first '   itemprop=\"image\" itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/ImageObject\" ><div class=\"avia-image-container-inner\"><div class=\"avia-image-overlay-wrap\"><img decoding=\"async\" fetchpriority=\"high\" class='wp-image-4690 avia-img-lazy-loading-not-4690 avia_image ' src=\"https:\/\/tmckolkata.com\/in\/wp-content\/uploads\/2021\/03\/IMG_1585-800x423.jpg\" alt='' title='IMG_1585'  height=\"423\" width=\"800\"  itemprop=\"thumbnailUrl\" srcset=\"https:\/\/tmckolkata.com\/in\/wp-content\/uploads\/2021\/03\/IMG_1585-800x423.jpg 800w, https:\/\/tmckolkata.com\/in\/wp-content\/uploads\/2021\/03\/IMG_1585-710x375.jpg 710w\" sizes=\"(max-width: 800px) 100vw, 800px\" \/><\/div><\/div><\/div><br \/>\n\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-km7dqku2-ccfa85a10072aebe002dd892f2b03a65\">\n.avia-image-container.av-km7dqku2-ccfa85a10072aebe002dd892f2b03a65 img.avia_image{\nbox-shadow:none;\n}\n.avia-image-container.av-km7dqku2-ccfa85a10072aebe002dd892f2b03a65 .av-image-caption-overlay-center{\ncolor:#ffffff;\n}\n<\/style>\n<div  class='avia-image-container av-km7dqku2-ccfa85a10072aebe002dd892f2b03a65 av-styling- av-hover-grow avia-align-center  avia-builder-el-22  el_after_av_image  avia-builder-el-last '   itemprop=\"image\" itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/ImageObject\" ><div class=\"avia-image-container-inner\"><div class=\"avia-image-overlay-wrap\"><img decoding=\"async\" fetchpriority=\"high\" class='wp-image-4689 avia-img-lazy-loading-not-4689 avia_image ' src=\"https:\/\/tmckolkata.com\/in\/wp-content\/uploads\/2021\/03\/IMG_1582-800x423.jpg\" alt='' title='IMG_1582'  height=\"423\" width=\"800\"  itemprop=\"thumbnailUrl\" srcset=\"https:\/\/tmckolkata.com\/in\/wp-content\/uploads\/2021\/03\/IMG_1582-800x423.jpg 800w, https:\/\/tmckolkata.com\/in\/wp-content\/uploads\/2021\/03\/IMG_1582-710x375.jpg 710w\" sizes=\"(max-width: 800px) 100vw, 800px\" \/><\/div><\/div><\/div><\/p><\/div>\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-sh9fk-b83935009371f1b3d1ef193551a5b188\">\n.flex_column.av-sh9fk-b83935009371f1b3d1ef193551a5b188{\nborder-radius:0px 0px 0px 0px;\npadding:0px 0px 0px 0px;\n}\n<\/style>\n<div  class='flex_column av-sh9fk-b83935009371f1b3d1ef193551a5b188 av_one_third  avia-builder-el-23  el_after_av_one_third  el_before_av_one_third  flex_column_div av-zero-column-padding  '     ><style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-km7a83tr-e5cc82f7f1434f95a1b4a604deeb54d5\">\n.iconbox.av-km7a83tr-e5cc82f7f1434f95a1b4a604deeb54d5 .iconbox_icon{\nbackground-color:#21759b;\n}\n<\/style>\n<article  class='iconbox iconbox_top av-km7a83tr-e5cc82f7f1434f95a1b4a604deeb54d5  avia-builder-el-24  avia-builder-el-no-sibling  main_color'  itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/CreativeWork\" ><div class=\"iconbox_content\"><header class=\"entry-content-header\" aria-label=\"Icon: &lt;strong&gt;Major annual workload:&lt;\/strong&gt;\"><div class='iconbox_icon heading-color avia-iconfont avia-font-entypo-fontello' data-av_icon='\ue823' data-av_iconfont='entypo-fontello'  ><\/div><h3 class='iconbox_content_title '  itemprop=\"headline\" ><strong>Major annual workload:<\/strong><\/h3><\/header><div class='iconbox_content_container '  itemprop=\"text\" ><p>1. Karyotyping &#8211; 750<\/p>\n<p>2. FISH<\/p>\n<p>(a) Liquid\/Hemat FISH &#8211; 1100<\/p>\n<p>(b) Solid Tumour FISH &#8211; 1000<\/p>\n<p>(c) Her2Neu &#8211; 3503Stress Cytogenetics\/Fanconis &#8211; 20<\/p>\n<p>3. Stress Cytogenetics\/Fanconis &#8211; 20<\/p>\n<p>4. Constitutional\u00a0Karyotyping &#8211; 10<\/p>\n<p><strong>Total (including Karyotyping &amp; FISH) &#8211; 3300 approximately annually.<\/strong><\/p>\n<\/div><\/div><footer class=\"entry-footer\"><\/footer><\/article><\/div>\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-9vcnz4-7c226f9b4f87f6bc674c8f8ed59970bf\">\n.flex_column.av-9vcnz4-7c226f9b4f87f6bc674c8f8ed59970bf{\nborder-radius:0px 0px 0px 0px;\npadding:0px 0px 0px 0px;\n}\n<\/style>\n<div  class='flex_column av-9vcnz4-7c226f9b4f87f6bc674c8f8ed59970bf av_one_third  avia-builder-el-25  el_after_av_one_third  el_before_av_hr  flex_column_div av-zero-column-padding  '     ><style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-km7djynd-f2eebb306e3b12feec5fb6a70536c4f4\">\n.iconbox.av-km7djynd-f2eebb306e3b12feec5fb6a70536c4f4 .iconbox_icon{\nbackground-color:#21759b;\n}\n<\/style>\n<article  class='iconbox iconbox_top av-km7djynd-f2eebb306e3b12feec5fb6a70536c4f4  avia-builder-el-26  avia-builder-el-no-sibling  main_color'  itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/CreativeWork\" ><div class=\"iconbox_content\"><header class=\"entry-content-header\" aria-label=\"Icon: &lt;strong&gt;Teaching programmes:&lt;\/strong&gt;\"><div class='iconbox_icon heading-color avia-iconfont avia-font-entypo-fontello' data-av_icon='\ue84f' data-av_iconfont='entypo-fontello'  ><\/div><h3 class='iconbox_content_title '  itemprop=\"headline\" ><strong>Teaching programmes:<\/strong><\/h3><\/header><div class='iconbox_content_container '  itemprop=\"text\" ><ul>\n<li>Fellowship program in Cytogenetics<\/li>\n<li>Annual Workshop on Basic Molecular Pathology<\/li>\n<li>Regular short term training program for pathologists<\/li>\n<\/ul>\n<\/div><\/div><footer class=\"entry-footer\"><\/footer><\/article><\/div>\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-m5hugfek-36e6a195c358a7e6a528c4246bf07427\">\n#top .hr.hr-invisible.av-m5hugfek-36e6a195c358a7e6a528c4246bf07427{\nheight:10px;\n}\n<\/style>\n<div  class='hr av-m5hugfek-36e6a195c358a7e6a528c4246bf07427 hr-invisible  avia-builder-el-27  el_after_av_one_third  el_before_av_font_icon '><span class='hr-inner '><span class=\"hr-inner-style\"><\/span><\/span><\/div>\n\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-m5huh5dg-686912a06f27fd5b7e1c33488dda54e8\">\n.av_font_icon.av-m5huh5dg-686912a06f27fd5b7e1c33488dda54e8{\ncolor:#21759b;\nborder-color:#21759b;\n}\n.avia-svg-icon.av-m5huh5dg-686912a06f27fd5b7e1c33488dda54e8 svg:first-child{\nstroke:#21759b;\nfill:#21759b;\n}\n.av_font_icon.av-m5huh5dg-686912a06f27fd5b7e1c33488dda54e8 .av-icon-char{\nfont-size:40px;\nline-height:40px;\n}\n<\/style>\n<span  class='av_font_icon av-m5huh5dg-686912a06f27fd5b7e1c33488dda54e8 avia_animate_when_visible av-icon-style- avia-icon-pos-center avia-iconfont avia-font-entypo-fontello avia-icon-animate'><span 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